From Harvard Gazette:
The Gazette spoke with Genetics Professor David Sinclair, director of Harvard Medical School’s Paul F. Glenn Center for Biology of Aging Research, and postdoctoral fellow Jae-Hyun Yang about the work and its implications for human health and lifespan.
GAZETTE: David, you have said that you believe the first person to live to 150 has already been born. Does this work change that and is it possible that many people who are going to live to 150 have already been born?
SINCLAIR: Over the last 20 years, there have been a number of molecules that have been found to retard the aging process, at least in animals, and potentially a couple of drugs that are in humans. That made me optimistic that somebody who might make it to 150 has already been born. In this paper, we’re showing it’s possible to reset the age of the body up to as much as 50 percent. And, when you can reverse aging and not just slow it down, then all bets are off. We now know you can reset the eye multiple times and restore vision in old mice — that was our Nature 2020 cover article. In this paper, we’re showing that we can reverse aging in other tissues as well, using the same technology. So, if you can reset the age of the body multiple times, I think it would be dangerous to set an upper limit.