From Daily Mail (caution: tabloid):

Andy Burnham could be poised to be the first prime minister to enter Downing Street with an openly Catholic faith – nearly 500 years after Henry VIII split from Rome.
The Greater Manchester mayor is currently contesting the Makerfield by-election with a view to returning to Westminster to oust Keir Starmer from office. If he is successful in his bid to replace Sir Keir as PM, the 56-year-old’s entry into No10 would raise some constitutional challenges.